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BREAST PROGNOSTIC PANEL
Breast Prognostic Panel: ER, PgR, Her2, Ki67, and p53 IVD antibodies
TEST CODE
1033
CPT CODE
88360(x5)
TRANSPORT TEMPERATURE AND STABILITY
10% Neutral buffered formalin vial or Paraffin block: room temperature indefinitely
Positively charged slides: room temperature 30 days
REJECTION CRITERIA
Specimens collected using alternative methods or specimens in formalin outside of the 6 – 72 hour window may not be rejected but may include a disclaimer on the final report
TRANSPORT CONTAINER / SPECIMEN
10% Neutral buffered formalin-fixed tissue OR formalin- fixed paraffin-embedded tissue OR seven positively charged slides with 4µm sections
TURN AROUND TIME
72 hours
COLLECTION
- Collect biopsy(ies) with care. Avoid crushing the specimen with forceps or other instruments.
- Place tissue in 10% neutral buffered formalin within one hour of excision.
- Notate on requisition the time of tissue collection and cold ischemic time.
- Label specimen container with two patient identifiers.
TEST SETUP
Monday – Friday (days)
METHODOLOGY
IHC with quantitative scoring
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